#BladderCancer Symptoms and How It Affects the Body

By Lucas Ramires Lord

Every year thousands of people die from cancer around the world. This disease affects different parts of the body including the bladder. In the United States alone, there are hundreds and thousands of cases of people with history of bladder cancer. Causes of the disease may vary from genetics to substances taken for a different health condition.

One of the most common bladder cancer causes recently recorded is the use of Actos. This is a drug used by people afflicted with Type II Diabetes. It controls your blood sugar and helps your body to better use the insulin it produces. It prevents unnecessary buildup of sugar in your bloodstream. While it helps people with diabetes in many ways, experts have found a link between the drug and bladder cancer. Symptoms of the fatal disease became more prevalent on those who used the drug in the past.

Pioglitazone or more known as the brand Actos, recently received a ban from the FDA. A few years ago, this medicine became a popular treatment for Type II Diabetes Mellitus. Today, you will not find the drug on the shelves of your local pharmacy store. While the research is continuous, many have died from the new disease they have acquired. Recent studies found that the risk of developing bladder cancer is 40% higher for people who regularly took the drug for two years.

You can file a complaint against the Actos manufacturer if you think you have been diagnosed with the disease because you used the drug in the past. Many others have done the same and requested for compensation. For this, you will need the help of a lawyer focused specifically on this case.

You are already a candidate for this type of cancer if you took the drug in the past. You might not realize it but you could be already experiencing some bladder cancer symptoms. Here are some of them.

Hematuria

Among all bladder cancer symptoms, this one you should never ignore. It is the discoloration of your urine because of blood. When this occurs, it is time to consult your doctor. Along with the darker color, you may experience discomfort while urinating.

Urinary tract Infection

This is a bacterial infection, which affects the urinary tract. It is a disease, which is more common in women than men. People can get this disease when they do not clean themselves well or control what they eat or drink. In this case, it can be in relation with Hematuria.

You may also experience frequent pain in your abdomen or lower back area. In some cases, you may notice a bump or mass forming on the pelvic area. When your condition worsens, you may notice a drastic loss of weight, anemia and pain all over the pelvic area.

Learn more about these bladder cancer symptoms when you visit your regular physician. Schedule an appointment and check-up to be sure if you have acquired the disease or not.

Lucas Lord is a health blogger who has written about bladder cancer causes and bladder cancer symptoms.

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Just What is Neurogenic #Bladder?

Bladder function is normally automatic but is governed by the brain.  The final decision on whether or not to void is lost in patients with a neurogenic bladder and symptoms may vary depending upon the cause and other associated conditions.  The sensory nerves in the bladder sense the fullness of the bladder and then the brain allows the motor nerves to trigger the muscle contraction of the bladder wall muscles which forces urine out through the urethera.

Neurogenic bladder is a condition that affects both males and females and can result from disease, injury, or birth defects that affect the brain, spinal cord, or nerves leading to the bladder.  Neurogenic bladder is caused by problems with the nerves carrying messages between the bladder and the brain which resdults in the loss of the normal bladder function control.

Bladder function is normally automatic but is governed by the brain.  The final decision on whether or not to void is lost in patients with a neurogenic bladder and symptoms may vary depending upon the cause and other associated conditions.  The sensory nerves in the bladder sense the fullness of the bladder and then the brain allows the motor nerves to trigger the muscle contraction of the bladder wall muscles which forces urine out through the urethera.

Neurogenic bladder refers to a condition when this signal is interrupted or disabled, usually due to a disease of the nervous system, brain tumors or other diseases of the brain, injuries or disease of the spinal cord, and conditions such as spina bifida.  Sometimes neurogenic bladder happens after a surgery in the pelvic region.  Neurogenic bladder gives a person difficulty in passing urine without the use of a catheter or other external method.

There are two types of neurogenic bladder; overactive which means a spastic or hyper-reflexive bladder and under active or hypotonic bladder.  With overactive bladder there is frequent and uncontrolled leaking or expulsion of urine from the bladder and typically reduced bladder capacity.  Involuntary release of large volumes of urine or continuous dribbling of small amounts are ongoing health issues and a cause of social embarsament.

With under active neurogenic bladder has a very large capacity for urine because it has a tendency to overfill.  This is because it does not have the normal contractions that a bladder should when it is full.

Treatment options for neurogenic bladder usually consist of intermittent or continuous catheterization.  Intermittent catheterization is done four to six times per day and avoids the complications that typically arise with continuous catheterization, such as infection due to a buildup of bacteria in the pelvic region.  Many patients who have use of their arms can learn to catheterize themselves, otherwise this procedure must be done by a healthcare professional.

Long-term management for neurogenic bladder includes controlling one's fluid intake, not just by the amount taken in but also according to how often one takes in fluids.  This way a patient can be more aware of when they need to empty their bladder and there are less occurrences of spontaneous emptying of the bladder and urine spillage.  A patient may also be taught how to use external pressure on the muscles or by stretching so as to empty their bladder on command.  Surgery is another treatment option for neurogenic bladder.  Doctors may implant what is known as an inflatable sphincter in the area of the bladder.

It is also important for patients with neurogenic bladder to continue the use of antibiotics so as to reduce the occurrences of infection in the area of the bladder, especially if he or she is using an external catheter.  Regular checkups are also needed so as to be sure that there are no such infections occurring.

Always consult your doctor before using this information.

This Article is nutritional in nature and is not to be construed as medical advice.

Foods to Prevent and Treat Cancers - #BladderCancer

Author: Kyle J. Norton

Phytochemials are defined as a group of chemical compound found naturally in plants, including fruits, vegetables, beans, grains, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
Can food intake can help to prevent and treat cancers?. Many studies have proven that they can because of certain phytochemicals, but for what ever reasons, there are either no clinical trials follow through or the studies can not make to stage of clinical trials. Do not expect the pharmaceutical or foods industrial companies to pay for the researches, as the discovery of the phytochemicals to cure cancers can only dampen the profits of both industries as phytochemicals can not be patented.

I. Bladder cancers
A. The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excreted them through the urethra.
Bladder cancer is most common type of cancer that effect men twice as frequently as it effects women. Usually it starts from the lining the bladder caused by several types of malignant growths of the urinary bladder cells.

B. Types of Bladder cancer
B.1. There are three types of bladder cancer beginning in cells in the lining of the bladder, classified due to their origination.
1. Transitional cell carcinoma
In early stage of bladder cancer, normal cells become cancerous in the innermost tissue layer of the bladder which can change shape and stretch without breaking apart as they are able to stretch when the bladder is full and shrink when it is emptied. More than 90 percent of bladder cancers begin in the transitional cells
2. Squamous cell carcinoma
Cancer begins in squamous cells in the found in the tissues of the surface of the bladder, due to long-term infection or irritation. About 8 percent of people with bladder cancers begin squamous cells
3. Adenocarcinoma
Cancer begins originates in glandular tissue of the bladder, including the surface layer of skin, glands and a variety of other tissue, due to long-term irritation and inflammation. Only 2 percent of people with the condition have a third bladder cancer type.

B. 2. Types of bladder cancer classified due to their proliferation
1. Superficial types of bladder cancer
This type of bladder cancers have a characteristic of often recurrence but usually non invasive. It can be controlled or removed by regular cystoscopy.
2. Invasive types of bladder cancer
Invasive types of bladder cancer tend to spread after beginning in cells in the lining of the bladder. It often requires surgery by removing part or whole bladder.

C. Types of Food to Prevent and Treat Bladder cancer
1. Soy
Soy phytochemicals have been associated with the protective effect against bladder cancer as it contains genistein, and the isoflavone-rich soy phytochemical concentrate (SPC). Dr. Singh AV and the research team at the Beth Israel Deaconess Medical Center, showed that Mice treated with genistin and SPC had reduced final tumor weights by 56% (P < 0.05) and 52% (P < 0.05), respectively, associated with induction of tumor cell apoptosis and inhibition of tumor angiogenesis in vivo. In addition, SPC treatment, but not genistin treatment, significantly inhibited lung metastases by 95% (P < 0.01) associated with significant down-regulation of NF-kappaB expression in tumor tissues and reduction of circulating insulin-like growth factor-I levels, suggesting that SPC may contain other bioactive ingredients that have antimetastatic activity(1).

2. Milk thistle seed
Silybin, a phytochemical, is aslo known as Silibinin (INN), the major active ingredient of silymarin, a flavanone, found in the milk thistle seeds has been studied for prevention and therapy of various human malignancies including bladder. In the investigation of silibinin and its effect on bladder cancer found that oral silibinin suppressed the growth of 5637 xenografts, which was accompanied with the activation of caspase-3, downregulation of survivin, and increased translocation of AIF. Furthermore, intravesical silibinin effectively inhibited the carcinogenesis and progression of bladder cancer in rats initiated by MNU by reducing the incidence of superficial and invasive bladder lesions without any side effects, which was accompanied with proapoptotic effects.(7)

3. Cruciferous vegetables
Isothiocyanates are derived from the hydrolysis (breakdown) of glucosinolates—sulfur-containing compounds found in cruciferous vegetables. Isothiocyanates (ITCs) are a class of well-known cancerpreventive phytochemicals. Dr. Tang L and scientists at the Roswell Park Cancer Institute, in the sudy to examine the anti-cancer activity of NAC-ITCs in cultured human bladder cancer cells. In this paper, we report that the NAC conjugates of four naturally occurring ITCs, including allyl ITC, benzyl ITC (BITC), phenethyl ITC and sulforaphane, potently inhibited the growth of cells derived from both low-grade superficial and high-grade invasive human bladder cancers and drug-resistant bladder cancer cells, indicated that both compounds also demonstrated the same anti-proliferative mechanisms: causing the cleavage of the same set of caspases (caspase-3, -8 and -9) in apoptosis induction, arresting cells in the same phases (S and G2/M) and targeting the same cell cycle regulator (Cdc25C), although a longer treatment time or slightly higher doses were needed for NAC-BITC to achieve the same effect as BITC, presumably due to slower cellular uptake of NAC-BITC. These data show that the NAC-ITCs are biologically similar to their parent compounds and are highly effective against human bladder cancer cells(3).

4. Garlic
Garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase have exerted the protective effect against human bladder tumor cells. Dr. Chung JG. at the China Medical College, in the study of Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human bladder tumor cells indicated that the viability, NAT activity and 2-AAF-DNA adduct formation in human bladder tumor cells was inhibited by DAS and DADS in a dose-dependent manner, i.e. the higher the concentration of DAS and DADS, the higher the inhibition of NAT activity and cell death(4).

5. Cranberry juice concentration
In the study to exam the chemopreventive efficacy of cranberry juice concentrate in an experimental model of urinary bladder cancer, using female Fischer-344 rats, fed with N-butyl-N-(4-hydroxybutyl)-nitrosamine (OH-BBN) for a period of eight weeks, DR. Prasain JK and the reseah team at University of Alabama, showed that the cranberry extract neither affected body weight gain nor caused other signs of toxicity. For the metabolic studies, serum and urine were collected at 4 and 12 h after the administration of the cranberry juice concentrate and were analyzed by LC-MS/MS. Quercetin and its methylated derivative were detected in the urine samples. However, no quercetin was detected in the serum samples, indicating its poor bioavailability. These data suggest that components of cranberries may be effective in preventing urinary bladder carcinogenesis(5).

6. Green tea
The ingredient of (--)-Epigallocatechin-3-gallate (EGCG) in green tea have exerted the protective effect to cause bladder cancer cell death. "EGCGs that were physically attached onto the surface of nanogold particles (pNG) was confirmed by scanning electron microscopy. The anticancer activity of the EGCG-adsorbed pNG was investigated in C3H/HeN mice subcutaneously implanted with MBT-2 murine bladder tumor cells. EGCG-pNG was confirmed to inhibit tumor cell growing by means of cell apoptosis" said Dr.Hsieh DS and the research team team at National Taiwan Ocean University(6).

7. Tomato Juice
The ingredient of lycopene and other anti-oxidants in combination found abundantly in tomato juice have exerted an inhibitory effect on the development of TCCs in the rat urinary bladder. In the study of male Fischer 344 rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) fed with 0.05% BBN in their drinking water for 8 weeks, followed by diluted tomato juice for 12 weeks, lycopene concentrations in the livers of rats given tomato juice were elevated. Histopathological analysis of urinary bladder lesions revealed the numbers, but not incidences, of urinary bladder transitional cell carcinomas (TCCs) to be decreased in the group given tomato juice(7).

8. Etc.

For the series of Foods to prevent and treat cancers, visit http://foodstopreventandtreatcancers.blogspot.ca/p/phytochemical-in-foods-to-prevent-and.html

For more health articles, please visit http://medicaladvisorjournals.blogspot.ca

Sources can be found at http://medicaladvisorjournals.blogspot.ca/2012/06/phytochemicals-in-foods-to-prevent-and.html

Article Source: http://www.articlesbase.com/nutrition-articles/foods-to-prevent-and-treat-cancers-bladder-cancer-5959875.html

About the Author

I have been studying natural remedies for disease prevention for over 20 years and working as a financial consultant since 1990. Health Researcher and Article Writer. Master in Mathematics and BA in World Literature and Literary criticism

Precursors and Threats Associated With #BladderCancer

Author: Trevor Price

There are two primary bladder cancer symptoms - a drastic change in urination habits or patterns, and blood in the urine. Unfortunately, many instances of this potentially deadly disease are still unrecognized in people's lives.

Approximately 54,300 new cases of bladder cancer are diagnosed in the U.S. every year, and over 12,000 people die of the disease. It is the sixth most common cancer in the country. And though the five-year survival rate sits at an impressive 81 percent, the chances for full recovery are dramatically improved if the disease is caught early.

That's the reason recognizing and diagnosing bladder cancer symptoms is crucial. So, if you're interested in learning more about the signs of bladder cancer and potential causes of the disease, read on.

Evidences and Signs Associated with Bladder Cancer

Bloody Urine: The primary symptom of bladder cancer is blood in the urine. While bloody urine can often be an indicator of other bladder problems (kidney cancer, kidney stones, bladder infections), it's almost always exhibited in patients diagnosed with bladder cancer.

Urination Patterns: Most people diagnosed with bladder cancer complain of a frequent urge to pee, possible urinary incontinence and difficulty making it through the night without having to use the bathroom multiple times. Unfortunately, most patients with bladder cancer are older and don't recognize this symptom as a potential indicator of a more serious problem.

Causes and Risk Factors Associated with Bladder Cancer

Smoking: Smokers are more than twice as likely to develop bladder cancer than nonsmokers. Smoking causes about half of the deaths from bladder cancer among men and over 30% of bladder cancer deaths among women.

The carcinogens in cigarettes make their way into the blood stream and finally through the bladder and into the urine, which is why they're such a major cause of bladder cancer.

Exposure at the Work Place: Aromatic amines, types of industrial chemicals which are often used in the dye industry, are considered a major cause of bladder cancer.

Other organic chemicals, like those used in rubber plants, leather manufacturers, fabrics and textiles and printing firms, are also a higher risk factor for the disease.

Race: Bladder cancer is typically more common in Caucasians than other races.

Age: The risk for developing bladder cancer increases with age. The average age for those diagnosed with the disease is around 68 years. Meanwhile, less than 1% of bladder cancer patients are age 39 and under.

Chronic Bladder Problems: Patients who have a long-term history of kidney stones, urinary infections, bladder stones or other forms of chronic bladder irritation may be at an increased risk for developing bladder cancer.

If the risk factors listed above apply to you, it's important that you be able to not only recognize bladder cancer symptoms (bloody urine, changing urination habits), but that you also act on them and seek the advice of a physician.

When confronted with symptoms of any form of cancer, you are much better off taking precautionary steps to ensure your health than to assume no problem while allowing something dangerous to spread through your body unchecked.

Article Source: http://www.articlesbase.com/cancer-articles/precursors-and-threats-associated-with-bladder-cancer-707672.html

About the Author
For helpful information on various cancers - please visit cancerinfotips.com - a popular site providing symptom and treatment insights - such as men's breast cancer - childhood osteosarcoma - and many more!

#BladderCancer in Studies

by Ian Gould

Bladder cancer research is now increasing with leaps and bounds as the number of patients is also on the rise. But like bladder cancer, the men's cancer - prostate cancer is also to be diagnosed early. The prostate test which detects a single cancer cell passing in urine should be encouraged for a better and healthy nation.

There can be a highly sensitive test whose accuracy is the best in the case of early cancer detection, providing an alternative to the conventional undesirable testing method. A new study suggests that this new method can have around 85% sensitivity but it cannot detect tiny tumors.

Urine sample analysis for diagnosing cervical cancer is like finding a drop of water in a river because cancer cells are generally hidden amidst a cloud of normal cells. Detection is even more difficult when the patient has kidney stones, bladder stones or urinary tract infection, as the bodies produce more normal cells. This whole method empowers the doctors with a high sensitivity for detection of cancer. Prostate cancer is relatively difficult as it gives out 100 times fewer cells.

Bladder cancer is very much curable if it is detected early. Needless deaths can be prevented if this new, non-invasive method proves to be highly accurate. And the diagnosis would be done through a urine test which is far more comfortable than an endoscopy inside the urinary tract - which many patients find to be uncomfortable, unpleasant and invasive. It is mandatory for patients with this disease to undergo the conventional test every 3-6 months as it has a high risk of recurrence.

Bladder Cancer patients should be aware of many things like breathing polluted air harms not only the lungs but also leads to bladder cancer or UBC - Urinary Bladder Cancer as it is called. Also, additives in processed meat like sausages and bacon could also increase the cancer risk. The slats like sodium nitrite and nitrate in spicy foods can form cancerous products while mixing with stomach acids during digestion. This new research study suggests that the risk for this disease could be up by 30%.

Bladder cancer patients should be aware about such new developments in the field which can either help them to reduce risk as they would know about different risks associated with cancer or either the new developmental progress to find cures whose alertness can be spread and supported by all those who are victimized by the disease.

I am ian gould and I want to write about cancer is very common problem people. Writing is my passion and I want to communicate with people in my article. I am interested in discussing stone in the bladder, cervical cancer, Bladder cancer, gastrointestinal cancer screening.